Phenylpropanoids and polyketides
Medchemexpress LLC (E)-Naringenin chalcone | 25515-46-2 | 25 MG
(E)-Naringenin chalcone is an orally active anti-allergic agent that exhibits antioxidant and anti-inflammatory properties. It can enhance adipocyte functions and inhibits the release of histamine from rat peritoneal mast cells.
- Anti-allergic agent: orally active and inhibits histamine release from rat peritoneal mast cells.
- Antioxidant activity: possesses antioxidant properties.
- Anti-inflammatory activity: demonstrates anti-inflammatory effects.
- Adipocyte function improvement: can improve the functions of adipocytes.
- PPARγ stimulation: stimulates the activity of PPARγ in NIH-3T3 cells.
- Inhibition of inflammatory mediators: inhibits the production of TNF-alpha, MCP-1, and nitric oxide (NO) by LPS-stimulated RAW 264 macrophages.
- Suppresses allergic asthma: inhibits the type-2 function of CD4 T cells in allergic airway inflammatory mice.
Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 25 G
4'-Methoxychalcone regulates adipocyte differentiation by activating PPARγ. It also modulates the expression and secretion of various adipokines in adipose tissue, which are involved in insulin sensitivity. The compound has shown antiproliferative activity against several human cancer cell lines, including A2780, CAL-51, HCT-116, and HT-29, and cytotoxicity against DLD-1 and FHC cells.
- Regulates adipocyte differentiation through PPARγ activation.
- Modulates adipokine expression and secretion in adipose tissue, impacting insulin sensitivity.
- Exhibits antiproliferative activity against human cancer cell lines.
- Cytotoxic to certain human cell lines.
- Originates from plants, specifically Piper nigrum Linn.
Medchemexpress LLC Pinostrobin chalcone | 18956-15-5 | 99.9% | 270.28 g/mol | C16H14O4 | 10 MG
Pinostrobin chalcone is a naturally occurring chalcone derivative supplied as a high-purity research standard for in vitro biological and analytical studies. It has reported cytotoxic activity against MDA-MB-231 and HT-29 cancer cell lines (IC50 = 20.42 ± 2.23 μg/mL and 22.51 ± 0.42 μg/mL). The compound is provided as a solid and should be stored sealed at 4°C, protected from moisture and light.
- High purity (99.94%).
- Molecular weight 270.28 g/mol.
- Chemical formula C16H14O4.
- CAS number 18956-15-5.
- Suitable for in vitro cytotoxicity and analytical assays.
- Provided in a 10 MG package for laboratory use.
- Store at 4°C, sealed, away from moisture and light.
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | 99.8% | 272.26 | 100 G
(±)-Naringenin | 67604-48-2 | 99.8% | 272.26 | 100 G
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 | C15H12O | 100g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | 99.8% | 272.26 | 5 G
(±)-Naringenin | 67604-48-2 | 99.8% | 272.26 | 5 G